Clinical Applications for AI Epic™ Co-Ablation System- Pancreatic Cancer

What is Cryotherapy for Pancreatic Cancer? Pancreatic cancer cryoablation is a minimally invasive therapeutic technique that offers a promising treatment option for select Pancreatic cancer cases. It utilizes extreme cold temperatures to destroy cancerous cells within the pancreatic gland while sparing as much healthy tissue as possible. This approach is particularly suitable for patients who are not candidates for surgical resection or conventional therapies. During the procedure, a thin, needle-like probe is precisely inserted into the pancreatic tumor. The probe delivers ultra-low temperatures, typically below -40°C, creating an ice ball that engulfs and destroys the cancer cells. Repeated freezing and thawing cycles induce cellular damage, ultimately resulting in targeted tumor necrosis.

Brand:

HYGEA

Model:

AI Epic™

Date:

27/08/2025

Category:

Key Advantages of Cryoablation in Pancreatic Tumor Treatment(1-4)

One key advantage of cryoablation is its ability to precisely target localized tumors, especially those not easily accessible through surgery or in patients with multiple small lesions. Additionally, cryoablation is generally well-tolerated and can often be performed on an outpatient basis.

The success of pancreatic cryoablation depends on factors such as tumor size and location. Smaller tumors near the pancreatic gland surface typically respond better to cryoablation, while larger or centrally located tumors near major vessels may require combination therapies or alternative approaches.

Precise and Controlled, Protecting Normal Lung Tissue

Cryoablation leverages real-time imaging such as CT to monitor ice ball formation, enabling precise tumor targeting and controlled ablation, while preserving surrounding healthy lung tissue and vital structures, thus minimizing damage and complications.

Stimulates Immune Response, and Supports Combination Therapies

The freezing process releases abundant tumor antigens that activate the patient’s immune system and enhance antitumor activity. Cryoablation also pairs well with chemotherapy, immunotherapy, radiotherapy, and other modalities to improve local and systemic outcomes.

Minimally Invasive, Safe, Fast Recovery, and Repeatable

Cryoablation is minimally invasive, causes mild postoperative pain, and supports fast recovery. It is suitable for elderly or frail patients and allows repeat treatments for recurrent or new tumors, offering high therapeutic flexibility.

References

1. Qian, Z., et al. (2022). The clinical and experimental study of ablation therapy combined with chemotherapy or chemotherapy alone in the treatment of stage IV pancreatic cancer. Journal of Nanjing Medical University (Natural Sciences), 42(6), 849–853. 2. Qian, Z. et al. (2021). The clinical study of intraoperative cryoablation therapy and intraoperative combined cryoablation and hyperthermia in the treatment of unresectable pancreatic cancer. Journal of Nanjing Medical University (Natural Sciences), 41(8), 1203–1207. 3. Luo, X.M. et al. (2016). Advances in cryoablation for pancreatic cancer. PMC, PMC4716077. 4. He, L. et al. (2017). Clinical Practice Guidelines for Cryosurgery of Pancreatic Cancer. PMC, PMC5555970. 5. Zhang, C. et al. (2024). Perioperative outcomes and long-term survival of cryosurgery on unresectable pancreatic cancer: a meta-analysis. PMC, PMC11254304.